Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine.

نویسندگان

  • D Capellà
  • J R Laporte
  • J M Castel
  • C Tristán
  • A Cos
  • F J Morales-Olivas
چکیده

Comment Both these patients were positive for HIV antibody and had a clinical and radiological presentation suggestive of P carinni pneumonia that responded to treatment; thus the criteria fbr a diagnosis of AIDS were satisfied. ' In case 2 the diagnosis was complicated by the previous amiodarone treatment, though pneumonitis induced by amiodarone is unusual at a daily dosage less than 400 mg.23 Chest infections are common in the elderly. The increasing incidence of HIV infection and a reluctance of older homosexuals to admit to at risk behaviour may mean that elderly patients will die without AIDS being diagnosed. In the United States 10% of patients with AIDS are over 50, 2-5% over 60, and 0 4% over 70. The table shows the age distribution of our patients with AIDS up to October 1987. Six of 235 (2 5%) patients were over 60. P carinii pneumonia should be considered in all patients with atypical chest infections, even when there are no apparent risk factors.

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Flunarizine and cinnarizine-induced parkinsonism: 25 years of de Melo-Souza's syndrome.

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عنوان ژورنال:
  • BMJ

دوره 297 6650  شماره 

صفحات  -

تاریخ انتشار 1988